Risk of bleeding in surgical patients treated with topical bovine thrombin sealants: a review of the literature

doi:10.1186/1754-9493-2-5

Patient Safety in Surgery

Volume 2

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Clark J
Crean S
Samudrala S

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Risk of bleeding in surgical patients treated with topical bovine thrombin sealants: a review of the literature

Matthew W Reynolds¹ , John Clark² , Sheila Crean¹ and Srinath Samudrala³

¹Epidemiology and Database Services, United BioSource Corporation, Medford, MA, USA

²Epidemiology and Risk Managment, United BioSource Corporation, Medford, MA, USA

³Institute for Spinal Disorders, Cedars-Sinai Medical Center, Los Angeles, CA, USA

author email corresponding author email

Patient Safety in Surgery 2008, 2:5doi:10.1186/1754-9493-2-5


Published:	18 March 2008

Additional files

Additional file 1:

Table 1. Risk of Bleeding Events in Published Surgical Studies (1997–2007). Table 2. Risk of Bleeding Events in Published Surgical Studies of Bovine Thrombin (1997–2007). These tables show the studies examined looking at bleeding events of surgical studies broken down by author, year, surgery type, number of patients, study design, definition of bleeding event, and risk of bleeds

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